Selected Publications
H. Bauer, N. Véron, J. Willert, B.G. Herrmann. (2007) The t complex-encoded guanine nucleotide exchange factor Fgd2 reveals that two opposing signaling pathways promote transmission ratio distortion in the mouse. Genes & Dev 21, 143-147.
L. Wittler, E. Shin, P. Grote, A. Kispert, A. Beckers, A. Gossler, M. Werber, and B. G. Herrmann (2007) Msgn1 expression and presomitic mesoderm maturation are controlled by synergistic activity of Wnt3a and Tbx6. EMBO Reports 8, 784-789.
Müller H, Fogeron M-L, Lehmann V, Lehrach H and Lange BMH. (2006) A Centrosome-Independent Role for γ-TuRC Proteins in the Spindle Assembly Checkpoint. Science, 314: 654-656.
J. K. Dale, P. Malapert, J. Chal, G.Vilhais-Neto, M. Maroto, T. Johnson, S. Jayasinghe, P. Trainor, B. Herrmann, and O. Pourquie. (2006). Oscillations of the Snail Genes in the Presomitic Mesoderm Coordinate Segmental Patterning and Morphogenesis in Vertebrate Somitogenesis. Developmental Cell 10, 355–366.
Muzny DM, Scherer SE, Kaul R, Wang J, Yu J, Sudbrak R, Hennig S, Kube M, Lehrach H, Reinhardt R, Gibbs RA et al. (2006) The DNA sequence, annotation and analysis of human chromosome 3. Nature. 440(7088): 1194-1198.
Herwig R, Lehrach H. (2006) Expression profiling of drug response - from genes to pathways. Dialogues Clin Neurosci. 8(3): 283-293.
Adjaye J, Huntriss J, Herwig R, BenKahla A, Brink TC, Wierling C, Hultschig C, Groth D, Yaspo ML, Picton HM, Gosden RG, Lehrach H. (2005) Primary differentiation in the human blastocyst: comparative molecular portraits of inner cell mass and trophectoderm cells. Stem Cells. 23(10): 1514-1525.
Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, Stroedicke M, Zenkner M, Schoenherr A, Koeppen S, Timm J, Mintzlaff S, Abraham C, Bock N, Kietzmann S, Goedde A, Toksoz E, Droege A, Krobitsch S, Korn B, Birchmeier W, Lehrach H and Wanker E. (2005) A human protein-protein interaction network: a resource for annotating the proteome. Cell 122 (6): 957-968.
H. Bauer, J. Willert, B. Koschorz & B.G. Herrmann (2005). The t complex-encoded GTPase-activating protein Tagap1 acts as a transmission ratio distorter in mice. Nature Genetics 37, 969-973.
Klipp E, Herwig R, Kowald A, Wierling C and Lehrach H. (2005) Systems Biology in Practice. Wiley-VCH, Weinheim. (Monograph)
Ross MT, Grafham DV, Coffey AJ, Scherer S, McLay K, Muzny D, Platzer M, Howell GR, Burrows C, Bird CP, Frankish A, Lovell FL, Howe KL, Ashurst JL, Fulton RS, Sudbrak R, Hennig S, Reinhardt R, Lehrach H, Bentley DR et al. (2005) The DNA sequence of the human X chromosome. Nature. 434(7031): 325-37.
Watanabe H, Fujiyama A, Hattori M, Taylor TD, Toyoda A, Kuroki Y, Noguchi H, BenKahla A, Lehrach H, Sudbrak R, Kube M, Taenzer S, Galgoczy P, Platzer M, Scharfe M, Nordsiek G, Blocker H, Hellmann I, Khaitovich P, Paabo S, Reinhardt R, Zheng HJ, Zhang XL, Zhu GF, Wang BF, Fu G, Ren SX, Zhao GP, Chen Z, Lee YS, Cheong JE, Choi SH, Wu KM, Liu TT, Hsiao KJ, Tsai SF, Kim CG, OOta S, Kitano T, Kohara Y, Saitou N, Park HS, Wang SY, Yaspo ML, Sakaki Y. (2004) DNA sequence and comparative analysis of chimpanzee chromosome 22. Nature. 429(6990): 382-8.
Ralser M, Nonhoff U, Albrecht M, Lengauer T, Wanker EE, Lehrach H, Krobitsch S. (2005) Ataxin-2 and huntingtin interact with endophilin-A complexes to function in plastin-associated pathways. Hum Mol Genet. 14(19): 2893-909.
A. Aulehla and B. G. Herrmann (2004). Segmentation in vertebrates: clock and gradient finally joined. Genes & Dev 18, 2060-2067.
M. Hofmann, K. Schuster-Gossler, M. Watabe-Rudolph, A. Aulehla, B. G. Herrmann and A. Gossler (2004). WNT signaling, in synergy with T/TBX6, controls Notch signaling by regulating Dll1 expression in the presomitic mesoderm of mouse embryos. Genes & Dev 18, 2712-2717 .
Goehler H, Lalowski M, Stelzl U, Waelter S, Stroedicke M, Worm U, Droege A, Lindenberg KS, Knoblich M, Haenig C, Herbst M, Suopanki J, Scherzinger E, Abraham C, Bauer B, Hasenbank R, Fritzsche A, Ludewig AH, Bussow K, Coleman SH, Gutekunst CA, Landwehrmeyer BG, Lehrach H, Wanker EE. (2004) A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease. Mol Cell. 15(6): 853-65.
A. Aulehla, C. Wehrle, B. Brand-Saberi, R. Kemler, A. Gossler, B. Kanzler, and B. G. Herrmann. (2003) Wnt3a plays a major role in the segmentation clock controlling somitogenesis. Developmental Cell 4, 395-406.
Heiser V, Engemann S, Brocker W, Dunkel I, Boeddrich A, Waelter S, Nordhoff E, Lurz R, Schugardt N, Rautenberg S, Herhaus C, Barnickel G, Bottcher H, Lehrach H, Wanker EE. (2002) Identification of benzothiazoles as potential polyglutamine aggregation inhibitors of Huntington's disease by using an automated filter retardation assay. Proc Natl Acad Sci USA. 99 Suppl 4:16400-164006.
